### How to read your report {: .ui .center .aligned .header}

    Responses to medications depend on a host of factors, including, genetics,
age, sex, other medications and several other factors. Your physician will
advise you on the right medications considering all the relevant factors.

This report is presented in a user friendly language and format. The following tips will help you get the
best information value out of the report.

**1. What are the various metabolizer phenotypes?**

**Ultra Rapid metabolizers (UM)** are individuals with variants associated with elevated drug metabolism.

**Extensive metabolizers (EM)** are individuals with variants associated with normal drug metabolism.

**Poor metabolizers (PM)** are individuals with variants associated with poor drug metabolism.

**Intermediate metabolizers (IM)** are individuals with variants associated with moderate drug
metabolism.

**Normal metabolizers (NM)** are individuals with variants associated with normal rate of drug
metabolism.

**Indeterminate (IN)** means that your metabolizer status could not be determined.

**2. Where did the information contained in the report come from?**

The information presented in this report is curated by our team of scientists from various high authority
sources such as the Clinical Pharmacogenetics Implementation Consortium (CPIC), the Royal Dutch
Association for the Advancement of Pharmacy - Pharmacogenetics Working Group (DPWG),
the Canadian Pharmacogenomics Network for Drug Safety (CPNDS) and other professional societies
and sources.

**3. How do I understand the information in the report?**

The report is organized by the drug names and areas of use. For example, you will find, "ANALGESIC-
TRAMADOL" which means that the drug is Tramadol and its used as an analgesic. Right underneath,
you will find your "diplotype" (genetic type) and your Metabolizer status, indicated as NM, PM, EM, etc.,
(please see question 1 above).

**Explanation of terms used in the report:**

**Recommendations:** Drug recommendations based on your genetics

**Implications:** Implications for your therapy

**Evidence Level:** Classification of the reliability of evidence with 1 being the highest.

**Evidence Strength:** The strength of this recommendation based on evidence.

